Accutane, a leading brand of prescription acne-fighting medication, has been linked to devastating gastrointestinal complications in many users. The drug, known chemically as isotretinoin, has been available in the U.S. since 1982 for treatment of moderate to severe acne and has been taken by more than 20 million people, making it one of the best-selling drugs ever. Sadly, many teens and young adults used Accutane to reduce the appearance of unsightly acne and suffered severe injuries as a result.

In June 2009, Roche Pharmaceuticals, the maker of Accutane, said it was no longer making the drug due in large part to the increasing costs of defending lawsuits filed by users who were injured by Accutane.
The use of Accutane has been associated with the following types of gastrointestinal injuries:
From 1997 to 2002, the Food and Drug Administration received 85 reports of inflammatory bowel disease it associated with the use of Accutane. In nearly all the cases, the agency determined it was "high probable" or "probable" that Accutane had caused the patients to develop the disease.
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